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When the tip of sheath is occluded by the migration into small vessels, the large negative pressure through side port might easily aspirate the air through the 1-way valve of the main proximal port. Physicians should keep in mind of the structure of the catheter sheath. Patients with DNA-damage response genes (DDR)-related pancreas cancer ( or other DNA-damage related genes) may have improved outcomes secondary to increased sensitivity to DNA-damaging drugs (platinum chemotherapy/ poly ADP ribose polymerase (PARP)-inhibitors). However,
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