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Beyond this time, cyclin B/Cdk1 is really important for phosphorylation of a distinct subset of mitotic Cdk1 substrates that are necessary to finish cell division. Our results identify how cyclin A, cyclin B and Greatwall kinase coordinate mitotic progression by increasing levels of Cdk1-dependent substrate phosphorylation. © 2020 The Authors. Posted beneath the regards to the CC with 4.0 permit.It happens to be documented that M2 macrophage polarization plays a suppr