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Variables associated with WLSM decisions included a poor motor score (p 0.0001) and radiographic evidence of infarction (p = 0.02). We identified several early predictors with high PPV for poor outcome. Of these, lack of improvement in motor score during the initial 72 hours had the greatest potential for confounding from "self-fulfilling prophecy." Absence of PLR at 24 hours, IVH score = 20, and ICH volume = 53 ml predicted poor outcome without a statistically significant effect on WLSM decisions. More research is needed