https://www.selleckchem.com/pr....oducts/tuvusertib.ht
Unique coverage depth tends to improve with more input, but improvements are not consistent. Fluctuations in library complexity complicated variant detection using both standardized and clinical specimens, often resulting in technical replicates with vastly different estimates of variant allelic fraction. We conclude that depth of coverage with unique reads must be tracked in clinical NGS to ensure that sensitivity and accuracy are maintained. We evaluate the impact of the Graduated Driver Licensing (GDL) system introduced in Victori
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