https://www.selleckchem.com/pr....oducts/nesuparib.htm
For circadian medicine to influence health, such as when to take a drug or undergo a procedure, a biomarker of molecular clock phase is required--one that is easily measured and generalizable across a broad population. It is not clear that any circadian biomarker yet satisfies these criteria. We analyzed 24-h molecular rhythms in human dermis and epidermis at three distinct body sites, leveraging both longitudinal (n = 2 and population (n = 154) data. We applied cyclic ordering by periodic structure (CYCLOPS) to order the population