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Along the way, we develop a new methodology to compare deterministic model predictions with the stochastic behavior exhibited by the DEM simulations around the jamming transition.A facile synthesis of 2-phosphorylated 2H-chromenes has been accomplished herein via a Y(OTf)3-catalyzed dehydrative coupling of 2H-chromene hemiacetals with P(O)-H compounds. This protocol features low catalyst loading, mild reaction conditions, broad substrate scope and easy elaboration of the products.Lithium salts are commonly used as medication for Bipola