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Coptisine is a natural alkaloid compound and is known to have multiple beneficial effects including antioxidant activity. However, whether it can protect lung fibroblasts from oxidative damage has not been studied yet. To investigate the potential inhibitory effect of coptisine against oxidative stress in V79-4 lung fibroblast cells. V79-4 cells were treated with H O (1mM) in the presence or absence of coptisine (50 µg/ml), N-acetyl cysteine (NAC, 10mM) or zinc protoporphyrin IX (ZnPP, 10 µM) for the indicated times. The alleviating effe
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