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CONCLUSIONS In the Nepalese general population, marital transitions increase the odds of subsequent depression, especially among the female population. Results provide basic but essential vital health data that can guide clinicians to proactively plan sustainable healthcare both within South Asia and among many South Asians living in other places. BACKGROUND Depression is correlated with poor prognosis in patients with coronary artery disease (CAD). The goal of this meta-analysis was to assess the influence of depression on the risks of