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The expression of 467, 526, and 571 genes assessed at ≤ 3, 5 and 24h after IS, correspondingly, had been associated with bad 90-day mRS outcome (mRS ≥ 3), while 49, 100 and 35 genes at ≤ 3, 5 and 24h after IS had been associated with good mRS 90-day result (mRS ≤ 2). Poor results were connected with up-regulated genes or paths such as for example IL-6, IL-7, IL-1, STAT3, S100A12, severe stage reaction, P38/MAPK, FGF, TGFA, MMP9, NF-kB, Toll-like receptor, iNOS, and