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They are dın̄ (religion), nafs (life), nasl (progeny), `aql (intellect) and māl (wealth). To make this happen, the five principles should all be fulfilled before endorsement of an experiment just like the Chinese embryo alterations; Qaṣd (intention) which can be attained in this situation as it is designed to protect the embryo from HIV. Yaqın̄ (certainty) and Ḍarar (injury) weren't happy while they need strong clinical certainty for the