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6% vs. 0.7%, p = 0.034), myocardial infarction (7.1% vs. 1.8%, p less then 0.001), in-stent thrombosis (4.5% vs. 0.8%, p less then 0.001), and stroke (7.1% vs. 6.4%, p = 0.025). After adjusting for confounding factors, LMCA remains independently associated with higher 2-year myocardial infarction rate (HR = 2.585, 95% CI = 1.243-5.347, p = 0.011). Conclusion LMCA-targeted PCI is an independent risk factor for 2-year myocardial infarction in ACS patients. Copyright © 2020 Si-Da Jia et al.Background The saline-induced distal coronary pressu