https://www.selleckchem.com/pr....oducts/jak-inhibitor
Aldo-keto reductase 1B10 (AKR1B1 is a secretory protein that is upregulated in breast cancer. This case-controlled pilot study evaluated the serum level of AKR1B10 in healthy women and patients with a localized or metastatic breast cancer. AKR1B10 levels were measured by ELISA and IHC in several patient cohorts. Our data showed that serum AKR1B10 was significantly elevated in patients with localized (6.72 ± 0.92 ng/ml) or metastatic (7.79 ± 1.13 ng/ml) disease compared to cancer-free healthy women (1.69 ± 0.17 ng/ml) (p0.0