https://www.selleckchem.com/ph....armacological_epigen
Icariin (ICA) is the main active ingredient of Maxim (Berberidaceae), which is used in the immune, reproductive, neuroendocrine systems, and anti-aging. To evaluate the effect of ICA on natural aging rat. 16-month-old Sprague-Dawley (SD) rats were randomly divided into aging, low and high-dose ICA groups ( = 8); 6-month-old rats were taken as the adult control ( = 8). Rats were fed regular feed (aging and adult control) or feed containing ICA (ICA 2 and 6 mg/kg group) for 4 months. HE and Nissl staining were used to assess
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