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001) and radiotherapy (p = 0.007). Liver-specific SSI risk factors were smoking (p = 0.046), low albumin (p 0.001) and significant blood loss (p 0.001). The rate of organ/space SSI in patients with POPF was 47.7% and in patients without POPF 7.3% (p 0.001). Organ/space SSI rate was 43% in patients with bile leak and 10% in those without (p 0.001). The risk factors for SSI following pancreatic and liver resections are distinct from each other, with higher SSI rates after pancreatic resection. Pancreaticoduodenectomy has