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All healthcare professionals, especially nurses, are affected psychosocially due to reasons such as uncertainty and work intensity experienced during the COVID-19 pandemic. In this descriptive study, it was aimed to determine the stress, depression and burnout levels of front-line nurses. Data were obtained from 705 nurses who worked at hospitals during the COVID-19 pandemic between May and July 2020, using a Personal Information Form, the Perceived Stress Scale, Beck Depression Inventory and Maslach Burnout Inventory. The data collection