What Causes Trucking Accidents? Trucks account for a small percentage of vehicles on the road, but they can be dangerous and cause serious injury or even death. Accidents involving large vehicles may be caused by drivers who are distracted or do not pay attention to their blind spots. Trucking accidents can be caused by driver fatigue. Drivers often work long hours, without breaks, to meet their quotas. Driver Error Trucking accidents are caused by driver error which is a grave problem. Driver errors can be caused by a variety of reasons. It