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turing understory plant communities that overwhelms abiotic factors. However, while exclosures prove useful to assess overall effects of large herbivores, the results from our studies at broader scales on the archipelago, suggest that exclosure experiments should be used cautiously when inferring the mechanisms at work. The driver genes play a key role in the evolutionary process of cancer. Effectively identifying these driver genes is crucial to cancer diagnosis and treatment. However, due to the high heterogeneity of cancers, it remains