https://www.selleckchem.com/pr....oducts/pemigatinib-i
Pavlovian-to-instrumental transfer (PIT) quantifies the extent to which a stimulus that has been associated with reward or punishment alters operant behaviour. In alcohol dependence (AD), the PIT effect serves as a paradigmatic model of cue-induced relapse. Preclinical studies have suggested a critical role of the opioid system in modulating Pavlovian-instrumental interactions. The A118G polymorphism of the gene affects opioid receptor availability and function. Furthermore, this polymorphism interacts with cue-induced ap
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