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Profilin 1 (PFN1), which will be expressed in both the embryo and in the endometrial epithelium, acts as a potent regulator of actin polymerization while the cytoskeletal system. In this research, we identified the precise part of endometrial PFN1 during embryo implantation. Practices Morphological alterations with respect to the status of PFN1 appearance were examined in PFN1-depleted or control cells grown on Matrigel-coated cover glass. Day-5 mouse embryos were cocultured with Ishikawa