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To evaluate the clinical efficacy of decoction (HQSJZD) for treating cancer-related fatigue (CRF) of spleen and stomach Qi deficiency type after chemotherapy in patients with breast cancer. A total of 94 breast cancer patients who developed CRF of spleen and stomach Qi deficiency type after chemotherapy were randomized into chemotherapy group ( =47) and traditional Chinese medicine (TCM) + chemotherapy group ( =47). The patients in chemotherapy group received the AC or EC regimen and non-drug interventions including psychological couns