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The analyses showed that longevity variants correlate with proteome signatures that could be manipulated to discover healthy-aging targets. Studies based on administrative databases show that infant pyeloplasty is associated with minority race/ethnicity but lack clinical data that may influence treatment. Our objective was to identify clinical and demographic factors associated with pyeloplasty in infants from three large tertiary centers. We reviewed infants with unilateral Society for Fetal Urology (SFU) grade 3-4 hydronephrosis seen at