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In transgenic mice with cardiac overexpression of kinase-dead mutant Mst1 gene, these damaging cardiac effects of DOX had been substantially attenuated relative to wild-type littermates. Conclusions Anti-cancer activity of both DOX and verteporfin is involving Hippo pathway activation. Such activity on cardiac Hippo path mediates mitochondrial harm and cardiomyopathy.Computed tomography (CT), a diagnostic device with clinical application, extensive protection, and low-cost, ca
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