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905 (95% CI 0.855-0.956), which was greater than sCD163, PCT, and HS-CRP detected alone. Combined detection of sCD163 with PCT and HS-CRP has a high diagnostic efficiency for early infection in patients with gynecological malignant tumors and fever, which is better than that of sCD163, PCT or HS-CRP alone. It can be used as an effective auxiliary examination method and an indicator for differential diagnosis. Key Words sCD163, PCT, HS-CRP; Gynecology, Tumor, Infection, Diagnosis. Combined detection of sCD163 with PCT and HS-CRP has a hig