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Eighteen days after DEN, an individual intraperitoneal dosage of Fe-NTA (5 mg Fe/kg) was administrated to rats to market nephrotoxicity. The biochemical variables were examined in serum at time intervals as the malondialdehyde (MDA) and tumor necrosis factor-alpha (TNF-α) were considered both in serum and renal areas. Kidney from each group had been histopathologically examined at time intervals. The management of Fe-NTA after DEN dosage to albino rats resulted in intense nephrotoxicity that was