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Conversely, adherence to PC2 (Mediterranean-like) was not related to cfPWV values (-0.18, 95% CI -0.36, 0.004; p=0.06). Likewise, MedS and other PC patterns did not show any significant association with cfPWV. Mediation analysis showed that the association between Western-like dietary pattern and cfPWV is mediated by higher levels of leucocytes (9.2% of the effect, p=0.047). Our study in a Southern European population identified a Western-like dietary pattern associated with an increased cfPWV, a proxy of arterial stiffness. The associatio