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Extracts from cellulose- and starch-based materials generally triggered a strong in vitro toxicity and contained most chemical features. The toxicological and chemical signatures of polyethylene (Bio-PE), polyethylene terephthalate (Bio-PET), polybutylene adipate terephthalate (PBAT), polybutylene succinate (PBS), polylactic acid (PLA), polyhydroxyalkanoates (PHA) and bamboo-based materials varied with the respective product rather than the material. Toxicity was less prevalent and potent in raw materials than in final products. A compari