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This study aimed to investigate the risk factors and prognostic value of anxiety and depression in glioma patients. A total of 190 glioma patients who underwent resection were consecutively enrolled. Anxiety was assessed using hospital anxiety and depression scale (HADS) and Zung self-rating anxiety scale (SAS); depression was assessed with the use of HADS and Zung self-rating depression scale (SDS). All patients were followed up to death or 36 months. Overall survival (OS) was calculated according to the survival data. The prevalence