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Immune stimulation experiment with bacterial endotoxin and a viral mimic revealed PmCdk-7 response to pathogenic stress. The results from our study showed that PmCdk-7 performs a vital function during the cell cycle by aiding DNA replication and also aid response to inflammations generated due to the incision from the grafting operation and long exposure to immune-stimulants (pathogens). IκB kinase (IKK) is the core regulator of the nuclear factor-κB (NF-κ pathway, which is involved in cellular development and proliferation, as