https://mdm2signals.com/index.....php/%ce%b2-lapachone
Salt inducible kinases (Siks) tend to be evolutionarily conserved genes involved in diverse biological procedures, including sodium sensing, metabolic rate, muscle tissue, cartilage and bone tissue development, but their part in development stays mostly unknown. Present conclusions implicate Siks in mitotic control, and in both cyst suppression and development. Utilizing a tumor design in the Drosophila eye, we show that perturbation of Sik function exacerbates tumor-like muscle