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In this analysis, the present issues and lasting accomplishments when you look at the improvement bioprosthetic products on the basis of the mammalian pericardium tissue, geared towards a wide-spectrum application in reconstructive surgery are examined. The basic technical ways to preparation of biocompatible forms providing continuous functioning, optimization of biomechanical and functional properties, and medical applicability are explained. © 2020 WILEY-VCH Verlag GmbH &