https://www.selleckchem.com/pr....oducts/17-AAG(Geldan
Finally, we used isobologram analysis to compare combinations of the ELQs with either proguanil or atovaquone. We show that all quinolone combinations with proguanil are synergistic against P falciparum However, against P knowlesi, no evidence of synergy between proguanil and the quinolones was found. Importantly, combining the novel quinolone ELQ-300 with atovaquone, was synergistic against both species. Our data identify potentially important species differences in proguanil susceptibility and its interaction with quinolo
Gefällt mir
Kommentar
Teilen
