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g., NiR, R700, and R80 are efficient, which induce the red shift of fluorescence. On the other hand, ultrafast photoinduced electron transfer from dyes (e.g., ICG, AG, and AV) to the fluorescent cage can induce fluorescence quenching. This study provides an insight into the construction of artificial photofunctional systems with energy and electron transfer functions via a host-guest approach in solution. The aim of this study was to evaluate the performance of a comprehensive diagnosis program called "Reuma-check" for the diagnosis of