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I recently got off 0.05% Tretinoin for almost 2 weeks and I just started using 0.3% Adapalene. Will I experience another purge like I did with Tretinoin? - Quora
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I recently got off 0.05% Tretinoin for almost 2 weeks and I just started using 0.3% Adapalene. Will I experience another purge like I did with Tretinoin? - Quora

Answer (1 of 3): Switching from 0.05% tretinoin to 0.3% adapalene may lead to another purging phase, similar to what you experienced with tretinoin. This happens because both medications increase cell turnover, which can initially bring underlying im