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Conclusion Compassion fatigue is more serious in emergency department nurses, and the incidence of workplace violence is higher. Workplace violence has a positive effect on compassion fatigue. Nursing managers should actively prevent workplace violence and improve the working environment, thus reducing empathy fatigue.Objective To explore the influencing factors of job burnout of medical staff and provide reference for the formulation of intervention measures. Methods From November to December, 2018, a questionnaire survey was conducted