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The hybrid Cu-hydroxyapatite-MWCNT composite revealed better antibacterial ability than HA/MWCNT for both gram positive and gram-negative bacteria with a maximum inhibition zone of 13-17 mm, compared with hydroxyapatite/f-MWCNT. The antibacterial ability of the Cu-hydroxyapatite/f-MWCNT nanocomposites was effective against Escherichia coli compared with other microorganisms. The Cu-hydroxyapatite/f-MWCNT nanocomposite exhibited that the coated material is nontoxic, biocompatible and suitable for biomedical application.The current investig