https://www.selleckchem.com/pr....oducts/cilengitide-e
Anti-FnEDA mAbs accumulated in diseased tissue at pharmacologically relevant concentrations, the targeting was sustained for up to 14days and FnEDA was able to support targeting of multiple doses of anti-FnEDA mAbs given 5days apart. FnEDA is specifically upregulated in the inflamed tissues of mCIA. Antibodies specific for FnEDA can be useful as molecular delivery vehicles for disease specific targeting of payloads to inflamed joint tissue. FnEDA is specifically upregulated in the inflamed tissues of mCIA. Anti
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