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and it enables the identification of gaps for the evaluation of existing and the development of new algorithms. This systematic review provides a comprehensive overview of applications of wearable inertial sensors to quantify everyday life motor activity in people with mobility impairments. It summarizes the state-of-the-art, it provides quick access to the relevant literature, and it enables the identification of gaps for the evaluation of existing and the development of new algorithms. The role of nuclear receptors in both the ae