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https://www.selleckchem.com/pr....oducts/apocynin-acet
001). Downstaging by 3 stages was the strongest independent predictor of overall survival (hazard ratio 0.17; 95% confidence interval 0.062-0.44). Overall survival was significantly better among patients in the ypTNM groups when a stage-by-stage comparison was performed with the pTNM group. Pathological stage is a more accurate predictor of prognosis compared clinical stage with downstaged patients benefiting from lower recurrence rates and improved overall survival. Patients downstaged due to neoadjuvant chemotherap