https://www.selleckchem.com/pr....oducts/jnk-inhibitor
01). GSZD decreased RANKL, and the number of osteoclasts (OCs) in joint tissues ( 0.01) and increased osteoprotegerin levels ( 0.01). GSZD inhibited RANKL-induced RAW264.7 differentiation and reduced bone resorption by OCs. GSZD upregulated IκB ( 0.01) and p65 ( 0.01) in the cytoplasm and downregulated p65 ( 0.01) in the cell nucleus. decoction has an anti-RA effect, suggesting its possible use as a supplement and alternative drug therapy for RA. Guizhi-Shaoyao-Zhimu decoction has an anti-RA effe
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