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In intergroup comparisons, nimesulide showed better effects than ibuprofen at 24, 48, and 72 postoperative hours, demonstrating a higher overall preemptive effect. No differences were observed in relation to the number of rescue medication. Preemptive administration of nimesulide showed better overall preemptive effects on postoperative pain control when compared with ibuprofen. Preemptive administration of nimesulide showed better overall preemptive effects on postoperative pain control when compared with ibuprofen.Adverse drug reactio
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