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MS and LB, the primary bacteria groups responsible for dental caries, and high levels of these bacteria in the mother promote transmission from mother to infant. The aim of this study was prevention of maternal MS and LB transmission on infants by using different preventive strategies and inhibition of early childhood caries proggession. This study was conducted with 50 mother-child pairs who were randomly allocated into either a study group or a control group (n = 25 each). Mothers in the study group were enrolled in a detailed prevent