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ts' QOL compared with adolescents with similar levels of H/I behaviors but no ADHD diagnosis. ADHD diagnosis was associated with worse scores in some outcomes, including significantly increased risk of self-harm. A large, randomized clinical trial with long-term follow-up is needed. Understanding whether prevention advertisements reduce susceptibility to vaping is important owing to concerning levels of adolescent vaping. To examine whether vaping prevention advertisements from the US Food and Drug Administration (FDA) national Real Cos