https://www.selleckchem.com/pr....oducts/alw-ii-41-27.
Furthermore, neither gout nor the prescription of allopurinol had a significant effect on the time to renal death (composite end point of kidney replacement therapy or death). Hyperuricaemia seemed to be independently associated with faster CKD progression or renal death. This was not observed with gout or prescription of allopurinol. Furthermore, allopurinol was not associated with decreased incidence ofcardiovascular events. These data suggest that hyperuricaemia is likely the effect and not the cause of CKDor CKD progression. Hy