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Overexpression of IIGP1 limited RABV replication in cell lines and paid off viral pathogenicity in a mouse design. Regularly, lack of IIGP1 improved RABV replication in different components of mouse brains. Furthermore, we discovered that IIGP1 could tion of P necessary protein. Our study gives the first research that IIGP1 functions in limiting viral illness and offers a basis for comprehensive knowledge of this important ISG.The humoral protected response against porcine reproductive and