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Copyright © 2020 Kelsey Ragan et al.Rheumatoid arthritis (RA) is one of the most predominant autoimmune diseases and a prototypic inflammatory illness, impacting the little joints for the fingers and foot. Chemokines and chemokine receptors perform a crucial role in RA pathogenesis via resistant cells recruitment. Several chemokines and chemokine receptors are abundant in the peripheral blood as well as in the local swollen bones of RA. Also, synthetic and biologics disease alterin