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05). Central nervous syndrome abnormalities (odds ratio [OR] = 20.9, 95% CI 4.3, 10, body temperature ≥ 38.5°C (OR = 23.2, 95% CI 3.4, 158), BUN levels ≥ 6.4 mmol/L (OR = 9.9, 95% CI 2.2, 44), CKMB levels ≥ 100 U/L (OR = 33.2, 95% CI 5.8, 192), and LDH levels ≥ 1,000 U/L (OR = 8.3, 95% CI 1.9, 37) were predictors of mortality. Our findings reveal that the presence of specific complications and laboratory parameters may serve as predictors of mortality and aid in early identification of severe SFTS cases in clinical practice. Emergency la