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GO and KEGG analyses were utilized to determine the likely function of the genes involved. Also, we evaluated the functional need for solitary nucleotide polymorphisms making use of RegulomeDB and GTEx. Seven qualified researches involving 29 genetics and 89 SNPs were reviewed in this review. We unearthed that the polymorphisms in gene NOS2, NOG, BMP4, CYR61, IL1β and FGFR1 evidently predisposed patients to fracture non-union, whilst the polymorphisms in gene
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