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In this work, three isostructural metal-organic frameworks based on first line change steel ions and 2-aminoisonicotinate (2ain) ligands, particularly, n [MII = Co (1), Ni (2), Zn (3)], are evaluated for their sensing ability of varied solvents and metal ions by monitoring the modulation of their magnetic and photoluminescence properties. The crystal framework comprises of an open diamond-like topological 3D framework that simply leaves huge voids, which all