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c antispasmodic drugs. Surveillance No consensus exists regarding the frequency of clinical follow-up visits, but reevaluation once or twice yearly to identify and treat new complications is recommended. Agents/circumstances to avoid Dantrolene, as it can induce irreversible weakness, adversely affecting mobility. Genetic counseling ATL1-HSP is almost exclusively inherited in an autosomal dominant manner. More than 95% of individuals diagnosed with SPG3A have an affected parent; the proportion of individuals with ATL1-HSP caused by a de no