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To evaluate the prognostic value of neutrophil-lymphocyte ratio (NLR) inrectal cancer patients treated with preoperative chemoradiotherapy (CRT) and curativesurgery. A comprehensive search of the EMBASE and PubMed databases was performed to screen studies that compared treatment outcomes according to the pre-CRT and/or post-CRT NLR in patients receiving preoperative CRT and curative surgery for locally advanced rectal cancer. Hazard ratios (HRs) for disease-free survival (DFS) and/or overall survival (OS) were extracted, and a random-effec